Short version: not reliably — and the attempt is where people actually get hurt. But there's a reason this search is so popular, and it deserves a straight answer rather than a lecture. Here's what the home remedies do, what they don't, and what the real treatment looks like (it's cheaper and shorter than most people expect).
What people usually mean
Nearly every "natural deworming" protocol is built on the same three herbs: wormwood, black walnut hull and clove, often with pumpkin seed, garlic or oregano oil alongside — the same foods sold as parasite-killers. It's an old combination with a long folk history.
Here's the honest state of the evidence: there are no published randomized controlled trials showing that triad clears intestinal parasites in humans. Not "the studies are mixed" — they largely haven't been done.
The risks that don't get mentioned
These are herbs, not inert food, and each has documented cautions:
Wormwood contains thujone, which can lower the seizure threshold. It may also stimulate uterine contractions — so it's avoided in pregnancy and with seizure disorders.
Black walnut is a tree nut (an allergy risk) and can increase bleeding risk if you take blood thinners.
Clove carries the same bleeding-risk caution alongside anticoagulants.
All of them are processed by the liver and kidneys, so caution applies with liver or kidney problems.
The one that genuinely worries doctors: online guides that tell you to take prescription antiparasitics like ivermectin or mebendazole without a diagnosis. These drugs are matched to specific parasites. Taking them blind risks side effects and interactions while whatever's actually causing your symptoms goes unexamined.
What actually works — and why it's not a big ask
People reach for home remedies partly because they imagine the alternative is expensive and grim. It usually isn't:
Testing identifies the parasite. An ova-and-parasite (O&P) stool test is the practical alternative to guessing. One thing to check before ordering, though: the cheapest option is often the least sensitive. A basic O&P finds Giardia only two-thirds to three-quarters of the time, and rarely finds Cryptosporidium at all without a special stain. If you are paying for a test, pay for one that includes antigen or PCR. And if pinworm is what you suspect, a stool test is the wrong test entirely — that one needs tape.
Treatment is targeted and short. Many worm infections clear with a single dose or a brief course of the right medication.
Pinworms — the most common of all — are often handled with medication available over the counter, plus a repeat dose about two weeks later and a hot wash of bedding.
Worth knowing: one negative stool test doesn't fully rule a parasite out, because some are shed intermittently. If symptoms persist after a negative, that's a reason to re-test rather than to start experimenting.
If you're going to do something at home anyway
Then do the things that actually carry evidence, none of which involve dosing yourself:
Hand-washing — the single biggest lever, especially with children in the house
Hot-washing bedding and underwear during a pinworm treatment; keep nails short
Safe water, cooked meat and fish, washed produce, shoes on contaminated soil
Rehydration if you've had diarrhea — dehydration is the real near-term danger
Educational only: this page is general information, not medical advice or a diagnosis. Never take prescription medication that wasn't prescribed for you, and speak to a doctor or pharmacist before using herbal products — particularly in pregnancy, for children, or alongside regular medication.
Where next?
Claims
“Die-off symptoms”
Why feeling awful isn't proof anything is working.